Company Filing History:
Years Active: 2007
Title: Inventor Spotlight: David D. McKee from Durham, NC
Introduction
David D. McKee, an esteemed inventor based in Durham, North Carolina, has made significant contributions to the field of biochemistry and molecular biology. With a focus on innovative methods in receptor biology, McKee has secured a patent that showcases his expertise and creativity in the laboratory.
Latest Patents
McKee holds a patent for a "Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same." This invention outlines a method for modifying a test nuclear receptor (NR) polypeptide. The patented methodology includes aligning a test NR polypeptide sequence with reference polypeptide sequences that have known X-ray structures, creating a three-dimensional model of the test NR, and identifying characteristic differences to facilitate targeted mutations. This advancement enhances the understanding of receptor interactions and holds potential for various applications in drug design.
Career Highlights
Currently, David D. McKee is affiliated with SmithKline Beecham Corporation, where he continues to push the boundaries of research in his area of expertise. His focus on nuclear receptor proteins and the methods of modifying them through structural biology has established him as a valuable asset within the scientific community.
Collaborations
Throughout his career, McKee has collaborated with several notable scientists, including Christopher J. Apolito and Randy K. Bledsoe. These collaborations have further advanced the research in molecular interactions and have laid the groundwork for innovative solutions in pharmacology and therapeutic development.
Conclusion
David D. McKee’s contributions to the field of receptor biology through his innovative patent exemplify the importance of such research in advancing medical science. His work at SmithKline Beecham Corporation, combined with valuable partnerships, highlights the collaborative nature of scientific discovery and the impact of dedicated inventors like McKee on future innovations.