Location History:
- Menlo Park, CA (US) (1993 - 1995)
- Palo Alto, CA (US) (1999 - 2005)
Company Filing History:
4 out of 40 
2 out of 415 
2 out of 82 
Years Active: 1993-2005
Title: The Innovative Contributions of David D. Lesikar
Introduction
David D. Lesikar is an accomplished inventor based in Palo Alto, California, who has made significant contributions to the field of pharmaceutical sciences. With a remarkable portfolio of nine patents, he has focused on developing solutions that address critical clinical challenges. His work showcases a deep understanding of biochemistry and innovative applications that can improve patient outcomes.
Latest Patents
One of David's notable patents is for "Protease Inhibitor Peptides." This invention pertains to analogues of the Kunitz Protease Inhibitor (KPI) domain of amyloid precursor protein, which bind to and inhibit the activity of several serine proteases, including kallikrein and coagulation factors such as factors VIIa, IXa, Xa, XIa, and XIIa. The pharmaceutical compositions containing these KPI analogues are designed to treat clinical conditions associated with increased serine protease activity, notably blood loss related to cardiopulmonary bypass surgery. This invention also includes nucleic acid sequences encoding these analogues and systems for their expression.
Another groundbreaking patent by David is for "Inhaleable Spray Dried 4-Helix Bundle Protein Powders." This invention provides highly dispersible spray-dried powder compositions specifically designed for aerosolized delivery to the lungs. The powders are produced under conditions that prevent protein aggregation while ensuring the particles are suitable for inhalation, exemplifying superior aerosol performance.
Career Highlights
David has brought his expertise to several organizations, notably Scios Nova, Inc. and Nektar Therapeutics. His work in these companies has helped propel advancements in therapeutic solutions, bridging the gap between laboratory research and practical applications. Through his innovative mindset, he has contributed to projects that promote significant benefits to healthcare.
Collaborations
Throughout his career, David has worked alongside esteemed colleagues such as R Tyler White and Deborah Damm. These collaborations have provided a synergistic approach to research and development, enhancing the potential impact of his inventions.
Conclusion
David D. Lesikar exemplifies the spirit of innovation in the pharmaceutical industry. His patents not only offer potential solutions for critical medical conditions but also reflect his dedication to improving health outcomes. As he continues to push the boundaries of invention, David remains a commendable figure in the realm of scientific advancements.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.