The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2005

Filed:

Mar. 14, 2003
Applicants:

Cynthia Stevenson, Mountain View, CA (US);

Jayne E. Hastedt, San Carlos, CA (US);

Russ Lehrman, Los Altos, CA (US);

Hi-shi Chiang, San Jose, CA (US);

David B. Bennett, San Jose, CA (US);

David Lesikar, Palo Alto, CA (US);

Bing Yang, Redwood City, CA (US);

David Gong, San Mateo, CA (US);

Kirsten Cabot, San Francisco, CA (US);

Inventors:

Cynthia Stevenson, Mountain View, CA (US);

Jayne E. Hastedt, San Carlos, CA (US);

Russ Lehrman, Los Altos, CA (US);

Hi-Shi Chiang, San Jose, CA (US);

David B. Bennett, San Jose, CA (US);

David Lesikar, Palo Alto, CA (US);

Bing Yang, Redwood City, CA (US);

David Gong, San Mateo, CA (US);

Kirsten Cabot, San Francisco, CA (US);

Assignee:

Nektar Therapeutics, San Carlos, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 912 ; A61K 914 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 α-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).


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