David C Polidori

Title: David C Polidori: Innovator in JAK Inhibitors and Autoimmune Treatments

Introduction

David C Polidori is a notable inventor based in Rancho Santa Fe, CA (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of small molecule inhibitors targeting the JAK family of kinases. With a total of 3 patents, his work has the potential to impact the treatment of various diseases.

Latest Patents

One of Polidori's latest patents involves a small molecule inhibitor of the JAK family of kinases. This invention discloses JAK inhibitors that exhibit low systemic toxicity. The methods outlined in this patent aim to treat disease states, disorders, and conditions mediated by JAK, including cancers of the stomach and intestinal system, such as colorectal cancers and familial adenomatous polyposis. Another significant patent focuses on compositions of peptide inhibitors of the interleukin-23 receptor (IL-23R). This invention relates to pharmaceutical compositions and methods for treating autoimmune inflammation and related diseases.

Career Highlights

Throughout his career, David C Polidori has worked with prominent companies in the pharmaceutical industry, including Janssen Pharmaceutica and Protagonist Therapeutics, Inc. His experience in these organizations has contributed to his expertise in drug development and innovation.

Collaborations

Polidori has collaborated with notable professionals in his field, including Giustino Di Pretoro and Dajun Sun. These collaborations have likely enhanced his research and development efforts.

Conclusion

David C Polidori is a distinguished inventor whose work in JAK inhibitors and autoimmune treatments showcases his commitment to advancing medical science. His contributions are poised to make a significant impact on the treatment of various diseases.