The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Mar. 09, 2022
Applicant:
Janssen Pharmaceutica NV, Beerse, BE;
Inventors:
Edward F. Attiyeh, Villanova, PA (US);
Kurtis E. Bachman, Chester Springs, PA (US);
Gerald C. Chu, Philadelphia, PA (US);
Tatiana Koudriakova, Poway, CA (US);
David C. Polidori, Rancho Santa Fe, CA (US);
Gary V. Borzillo, Upper Gwynedd, PA (US);
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 45/06 (2006.01); A61P 1/00 (2006.01); A61P 35/00 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 45/06 (2013.01); A61P 1/00 (2018.01); A61P 35/00 (2018.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Disclosed herein are JAK inhibitors that have low systemic toxicity. In some aspects, the disclosure includes methods for treating disease states, disorders, and conditions mediated by JAK, such as stomacho-intestinal system cancers, including colorectal cancers and familial adenomatous polyposis.