Location History:
- Stafford Springs, CT (US) (2010 - 2011)
- Vernon, CT (US) (2011 - 2013)
Company Filing History:
Years Active: 2010-2013
Title: The Innovative Contributions of David B Bolstad
Introduction
David B Bolstad is a notable inventor based in Vernon, Connecticut, who has made significant contributions to the fields of medicine and pharmacology. With a total of four patents to his name, Bolstad's work focuses on developing compounds with therapeutic properties that target various diseases.
Latest Patents
One of Bolstad's latest patents is titled "Inhibitors of dihydrofolate reductase with antibacterial antiprotozoal, antifungal and anticancer properties." This patent describes the design, synthesis, and testing of compounds that act as inhibitors of dihydrofolate reductase (DHFR). The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring linked to another substituted aryl, bicyclo, or heteroaryl ring. These DHFR inhibitors are potent and selective for various pathogenic organisms, including methicillin-resistant bacteria, fungi, and protozoa. Additionally, these compounds may also be effective against the mammalian enzyme, suggesting potential applications as anti-cancer therapeutics.
Another significant patent is for "Enantiomers of 2'-Fluoralkyl-6-nitroquipazine as serotonin transporter positron emission tomography imaging agents and antidepressant therapeutics." This patent involves racemic mixtures and individual enantiomers of fluorine-18 or carbon-11 radiolabeled 2'-alkyl-