Location History:
- West Newton, MA (US) (1995 - 2004)
- Newton, MA (US) (1998 - 2017)
Company Filing History:
22 out of 32 
3 out of 1,373 
1 out of 1,217 
Years Active: 1995-2017
Title: David A. Hafler: A Pioneer in Immunology and Patent Innovation
Introduction
David A. Hafler, based in West Newton, MA, has made significant contributions to the field of immunology, particularly focusing on T helper 17 (TH17) cells. With an impressive portfolio of 25 patents, Hafler's work has advanced the understanding of autoimmune diseases and the therapeutic potential of immune modulation.
Latest Patents
Hafler's latest patents include innovative methods for the selective differentiation, identification, and modulation of human TH17 cells. These inventions provide insights into how T17 cell differentiation is influenced by TGF-β and IL-21, along with their respective agonists and antagonists. Furthermore, his research has identified key markers for T17 cells, such as BLT1 and podoplanin, which are critical for the diagnosis and treatment of autoimmune diseases. Notably, one of his patents outlines methods for diagnosing autoimmune diseases like acute disseminated encephalomyelitis (ADEM), showcasing his commitment to tackling complex health challenges.
Career Highlights
Throughout his career, Hafler has held key positions at prominent organizations, including Autoimmune Inc. and Brigham and Women's Hospital. His roles within these institutions have enabled him to contribute to groundbreaking research and innovation in the immunology domain. His extensive experience has positioned him as a pivotal figure in translating scientific discoveries into practical applications that benefit patients.
Collaborations
Hafler's work often involves collaboration with other esteemed professionals in the field. Notable collaborators include Howard L. Weiner and Zhengyi Zhang, with whom he has partnered to enhance the understanding of immune responses and develop novel therapies. These collaborations have furthered the impact of Hafler's inventions and have been vital in advancing research in immunology.
Conclusion
David A. Hafler stands as an influential inventor whose patents and research have greatly impacted the field of immunology. With a focus on TH17 cells and autoimmune diseases, his contributions not only advance scientific understanding but also offer hope for more effective treatments. Hafler's commitment to innovation continues to inspire colleagues and aspiring inventors alike in their pursuit of groundbreaking solutions.