Cornwall, NY, United States of America

Darren Robert Abbanat

USPTO Granted Patents = 10 

 

 

Average Co-Inventor Count = 11.0

ph-index = 2

Forward Citations = 20(Granted Patents)


Location History:

  • Cornwall, NY (US) (2005 - 2024)
  • Cornwal, NY (US) (2022 - 2024)

Company Filing History:


Years Active: 2005-2025

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10 patents (USPTO):Explore Patents

Title: Darren Robert Abbanat: Pioneer in Bioconjugate Innovations

Introduction

Darren Robert Abbanat is an accomplished inventor based in Cornwall, NY, with a notable portfolio comprising ten patents. His groundbreaking work primarily focuses on bioconjugates and vaccine compositions aimed at combating extra-intestinal pathogenic (ExPEC) diseases.

Latest Patents

Among his latest innovations are two significant patents. The first, titled "Methods of producing bioconjugates of O-antigen polysaccharides, compositions thereof, and methods of use thereof," outlines methods for creating bioconjugates of O-antigen polysaccharides that are covalently linked to carrier proteins using recombinant host cells. These recombinant cells encode a specific oligosaccharyl transferase enzyme, which is essential for the bioconjugate production process. Enzymes such as PglB oligosaccharyl transferase or its variants are central to this innovative approach. The patent also encompasses compositions containing these bioconjugates, highlighting their potential application for vaccination against ExPEC.

The second patent, "Multivalent vaccine compositions and uses thereof," describes innovative compositions and methodologies for inducing an immune response against ExPEC. This research emphasizes the use of conjugates of polysaccharide antigen O75 attached to carrier proteins to provide immune protection against invasive diseases linked to ExPEC.

Career Highlights

Darren's career features significant contributions to prominent organizations within the pharmaceutical and biotechnology sectors. He has worked with Janssen Pharmaceuticals, Inc. and GlaxoSmithKline Biologicals S.A., where he has leveraged his inventiveness to advance bioconjugate technologies and vaccine development.

Collaborations

Throughout his career, Darren has collaborated with esteemed professionals, including his coworkers Michael T. Kowarik and Stefan Jochen Kemmler. These collaborations have undoubtedly contributed to the depth and breadth of his research and inventions.

Conclusion

Darren Robert Abbanat exemplifies innovation in the field of bioconjugate technology and vaccine development. His notable contributions and patents reflect his commitment to addressing significant health challenges posed by pathogens. Through his work, Darren continues to inspire future advancements in immunology and public health.

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