Company Filing History:
Years Active: 2016-2023
Title: Innovations by Inventor Danwei Guo in Nucleic Acid Analysis
Introduction
Danwei Guo is an innovative inventor based in San Mateo, California. With a focus on advancements in biotechnology, Guo has made significant contributions to the field of nucleic acid analysis, demonstrating expertise through his patented inventions.
Latest Patents
Guo holds two patents, the latest of which are focused on systems and methods for analyzing nucleic acid sequences. His inventions include nucleic acid sequence mapping and assembly methods that allow for the initial mapping of a contiguous portion of each read to a reference sequence. This process then extends mapping at both ends of the mapped portion to ensure the entire read is aligned. A key feature of his method is the calculation of a mapping score for alignment, which helps in ranking and selecting the best alignment for each read.
Another patent disclosed by Guo involves computational methods for translating a sequence of multi-base color calls into a base sequence. This innovative method involves encoding and sequencing a DNA sample using a multi-base code to produce a series of read color calls. Mismatches in alignment with a reference sequence are detected and corrected, leading to a decoded read sequence that retains the integrity of the original DNA fragment.
Career Highlights
Danwei Guo is a valued member of Life Technologies Corporation, where he applies his expertise to develop groundbreaking solutions in genetic analysis. His contributions have significantly advanced the methods used in the field and showcase his commitment to innovation.
Collaborations
Throughout his career, Guo has collaborated with notable colleagues, including Zheng Zhang and Yuandan Lou. These partnerships exemplify the collaborative spirit of innovation that drives advancements in biotechnology and genetic research.
Conclusion
With his inventive approaches to nucleic acid sequence analysis, Danwei Guo is making remarkable contributions to the field of biotechnology. His patents not only highlight his innovative spirit but also represent significant steps forward in the capabilities of genetic analysis technologies.