Danielle R Hawker

Title: The Innovative Contributions of Danielle R. Hawker

Introduction

Danielle R. Hawker is a notable inventor based in Shakopee, MN (US). She has made significant contributions to the field of biomolecule purification through her innovative work with porous metal oxides. Her research and inventions have the potential to enhance the efficiency of antibody purification processes.

Latest Patents

Danielle holds a patent for "High stability porous metal oxide spherules used for one-step antibody purifications." This invention describes the use of porous metal oxides for the preparative purification of antibodies and biomolecules. The patent outlines the characteristics of the particles, which typically range from 15 to 100 microns in average diameter, with pore sizes from 400 to 600 angstroms. The surface areas of these particles range from 10 to 50 square meters per gram, and pore volumes from 0.1 to 0.4 mL/gram can be utilized for purification processes. The metal oxide particles within this range exhibit enhanced utility and greater chromatographic capacity for antibodies compared to those outside of this range. Metal oxides such as zirconia, titania, and alumina can be modified with a multi-Lewis base moiety, such as organophosphate ethylenediamine-N,N-tetra(methylenephosphonic) acid (EDTPA), to create a bio-compatible purification media for biomolecules.

Career Highlights

Danielle is currently associated with Zirchrom Separations, Inc., where she continues to develop innovative solutions in the field of biomolecule purification. Her work has garnered attention for its practical applications in improving purification processes.

Collaborations

Danielle has collaborated with notable colleagues, including Clayton V. McNeff and Peter W. Carr, to advance her research and innovations in the field.

Conclusion

Danielle R. Hawker's contributions to the field of biomolecule purification through her innovative patent demonstrate her commitment to advancing scientific research. Her work has the potential to significantly impact the efficiency of antibody purification processes.