Daniele Pirone

Title: Daniele Pirone: Advancing Label-Free Identification of Subcellular Structures.

Introduction

Daniele Pirone is an inventor based in Baronissi, Italy, whose work includes computational methods for analyzing phase-contrast tomography. His patent focuses on identifying subcellular structures without chemical staining, using three-dimensional tomographic data.

Latest Patents

Pirone is associated with 1 patent: “Computer-Implemented Method and Corresponding Apparatus for Identifying Subcellular Structures in the Non-Chemical Staining Mode from Phase Contrast Tomography Reconstructions in Flow Cytometry.” The invention describes a computational segmentation method that uses statistical inference to identify subcellular structures directly from three-dimensional phase-contrast tomograms. It is designed for data produced by flow cytometry configurations and other experimental systems capable of generating quantitative phase-contrast tomograms.

Career Highlights

Pirone is associated with the Consiglio Nazionale delle Ricerche, Italy’s National Research Council. His patented work addresses a technical challenge in imaging and analysis: extracting information about subcellular structures from tomographic data without relying on chemical staining.

Collaborations

The patent’s listed collaborators include Pietro Ferraro and Pasquale Memmolo. Their work is connected to the development of computational approaches for interpreting phase-contrast tomography data.

Conclusion

Daniele Pirone’s patent presents a label-free computational approach to identifying subcellular structures, contributing to the analysis of three-dimensional phase-contrast images in flow cytometry and related systems.