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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12755566 B1

PDFFull Text
Date of Patent:
Oct. 06, 2026

Filed:

Jul. 19, 2022

Computer-implemented method and corresponding apparatus for identifying subcellular structures in the non-chemical staining mode from phase contrast tomography reconstructions in flow cytometry

Applicant:

Consiglio Nazionale Delle Ricerche, Rome, IT;

Inventors:

Pietro Ferraro, Naples, IT;

Daniele Pirone, Baronissi, IT;

Pasquale Memmolo, Regalbuto, IT;

Lisa Miccio, Piano di Sorrento, IT;

Vittorio Bianco, Naples, IT;

Demetri Psaltis, Preverenges, CH;

Joowon Lim, Renens, CH;

Assignee:

CONSIGLIO NAZIONALE DELLE RICERCHE, Rome, IT;

Attorney:

LUCAS & MERCANTI, LLP

Primary Examiner:

Amandeep Saini

Assistant Examiner:

Mehrazul undefined Islam

Int. Cl.
CPC ...
G16H 30/40 (2018.01); G01N 15/01 (2024.01); G01N 15/1429 (2024.01); G01N 15/1434 (2024.01); G06N 20/00 (2019.01); G06V 10/25 (2022.01); G06V 10/26 (2022.01); G06V 10/34 (2022.01); G06V 10/44 (2022.01); G06V 10/762 (2022.01); G06V 20/69 (2022.01); G16H 50/20 (2018.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G06V 20/695 (2022.01); G01N 15/01 (2024.01); G01N 15/1429 (2013.01); G01N 15/1434 (2013.01); G06V 10/25 (2022.01); G06V 10/273 (2022.01); G06V 10/34 (2022.01); G06V 10/443 (2022.01); G06V 10/762 (2022.01); G06V 20/698 (2022.01); G01N 2015/1006 (2013.01);
Abstract

The present invention relates to a computer-implemented method and corresponding apparatus for the accurate identification of subcellular structures from tomographic reconstructions. This invention allows to extract the 3D subcellular specificity directly from the tomographic phase-contrast data obtained from a typical flow cytometry configuration or any other experimental tomographic systems able to provide 3D quantitative phase-contrast tomograms. In particular, subcellular structures can be identified by using a novel computational segmentation method based on statistical inference from any 3D phase-contrast tomographic data.

Find Patent Forward Citations

Ferraro, Pietro. (2026). Computer-implemented method and corresponding apparatus for identifying subcellular structures in the non-chemical staining mode from phase contrast tomography reconstructions in flow cytometry (U.S. Patent No. 12755566). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12755566

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