Daniel P Knott

Title: The Innovations of Daniel P. Knott

Introduction

Daniel P. Knott is an accomplished inventor based in Shaker Heights, OH (US). He has made significant contributions to the field of tissue engineering, particularly through his innovative patents. With a total of 2 patents, Knott's work focuses on creating synthetic materials that can be used in various medical applications.

Latest Patents

Knott's latest patents include the development of a hydroxyphenyl cross-linked macromolecular network. This invention is particularly useful in artificial tissue and tissue engineering applications. It provides a synthetic macromolecular network suitable for a wide variety of tissue types, including artificial cartilage, vocal cord material, vitreous material, soft tissue material, and mitral valve material. The network is composed of tyramine-substituted and cross-linked hyaluronan molecules. Cross-linking is achieved via peroxidase-mediated dityramine linkages that can be performed in vivo. The dityramine bonds create a stable, coherent hyaluronan-based hydrogel with desired physical properties.

Career Highlights

Knott is associated with the Cleveland Clinic Foundation, where he continues to advance his research and innovations. His work has the potential to significantly impact the field of regenerative medicine and improve patient outcomes.

Collaborations

Some of his notable coworkers include Anthony Calabro and Lee Akst. Their collaborative efforts contribute to the ongoing research and development in the field of tissue engineering.

Conclusion

Daniel P. Knott's innovative work in creating synthetic tissue materials showcases his dedication to advancing medical technology. His contributions are paving the way for new solutions in tissue engineering and regenerative medicine.