Daniel J Wackelin

Title: The Innovations of Daniel J Wackelin

Introduction

Daniel J Wackelin is an accomplished inventor based in Pasadena, CA. He is known for his significant contributions to the field of enzyme catalysts, particularly through his work on cytochrome P450 variants. His innovative approach has opened new avenues for carbene insertion reactions, which are crucial in various chemical processes.

Latest Patents

Wackelin holds a patent for "Diverse carbene transferase enzyme catalysts derived from a P450 enzyme." This patent provides valuable insights into the use of cytochrome P450 variants for carrying out in vivo and in vitro carbene insertion reactions. The methods described in his patent include the preparation of carbene insertion products such as cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines.

Career Highlights

Wackelin is affiliated with the California Institute of Technology, where he has been able to leverage his expertise in enzyme catalysis. His work has not only contributed to academic research but has also had practical implications in the field of chemistry.

Collaborations

Throughout his career, Wackelin has collaborated with notable colleagues, including Kai Chen and Noah P Dunham. These collaborations have further enriched his research and have led to advancements in the understanding of enzyme functions.

Conclusion

Daniel J Wackelin's innovative work in enzyme catalysis exemplifies the impact of research on practical applications in chemistry. His contributions continue to influence the field and inspire future innovations.