The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2022
Filed:
Mar. 12, 2021
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Kai Chen, Pasadena, CA (US);
Noah P. Dunham, Pasadena, CA (US);
Daniel J. Wackelin, Pasadena, CA (US);
Andrew Z. Zhou, Pasadena, CA (US);
Zhen Liu, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12P 17/04 (2006.01); C12P 7/62 (2022.01); C12P 17/16 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0042 (2013.01); C12P 7/62 (2013.01); C12P 17/04 (2013.01); C12P 17/16 (2013.01); C12Y 106/02004 (2013.01);
Abstract
The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described.