Convent Station, NJ, United States of America

Daniel F Wyss


Average Co-Inventor Count = 7.0

ph-index = 1


Company Filing History:


Years Active: 2008

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1 patent (USPTO):Explore Patents

Title: The Innovations of Daniel F. Wyss in Hepatitis C Research

Introduction: Daniel F. Wyss, an inventor based in Convent Station, NJ, has made significant contributions to the field of hepatitis C research through his innovative work. With a focus on the NS3 helicase protein of the hepatitis C virus (HCV), Wyss has developed a vital patent that enhances our understanding of viral mechanisms and opens pathways for drug discovery.

Latest Patents: Wyss holds a patent for his invention titled “Hepatitis C virus NS3 helicase subdomain I.” This invention provides fragments of HCV NS3 helicase and crystalline compositions based on subdomains of the HCV helicase protein. The protein fragments developed are stable, soluble, and structurally sound, making them suitable for high-level expression in conventional expression systems. This capability is critical for enabling efficient large-scale production that can be used in NMR-based screening applications. Moreover, the helicase fragments offer vital resources for structural NMR studies and advanced drug discovery techniques such as SAR-by-NMR.

Career Highlights: Wyss's work at the Schering Corporation, a prominent player in pharmaceutical research, showcases his commitment to advancing medical science. His innovation in the production of protein fragments not only enhances the study of HCV NS3 helicase but also contributes to the ongoing battle against hepatitis C, a viral infection that poses significant health risks worldwide.

Collaborations: During his career, Wyss has had the opportunity to collaborate with esteemed colleagues, including Patricia C. Weber and Paul Reichert. Their joint efforts in research and development further amplify the impact of Wyss’s inventions, as they work together to unlock new possibilities for hepatitis C treatments.

Conclusion: Daniel F. Wyss stands as a notable figure in the realm of biomedical innovation, particularly in his dedicated efforts toward hepatitis C research. His contributions, underscored by his patent on the NS3 helicase subdomain, highlight the importance of collaboration in scientific advancements. As the fight against hepatitis C continues, Wyss's work serves as an essential building block for future therapeutic strategies.

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