Location History:
- Belchertown, MA (US) (2020 - 2023)
- Worcester, MA (US) (2024)
Company Filing History:
6 out of 1,551 
1 out of 2 Years Active: 2020-2025
Title: The Innovative Journey of Inventor Dan Wang
Introduction
Dan Wang, a prominent inventor based in Belchertown, MA, has made significant contributions to the field of gene therapeutics. With a total of five patents to his name, Wang's work primarily focuses on innovative solutions for treating bone disorders. His research and inventions are paving the way for novel therapies that target various bone-related conditions.
Latest Patents
One of Dan Wang's latest patents involves gene therapeutics for treating bone disorders. This patent details compositions and methods aimed at modulating bone mass in subjects. The disclosure includes isolated nucleic acids and vectors, such as rAAV vectors, specifically designed to express transgenes that can promote or inhibit the activity of bone cells like osteoblasts and osteoclasts. This groundbreaking work is particularly relevant for treating conditions associated with imbalances in bone mass, such as osteopetrosis and osteoporosis.
Another noteworthy patent from Wang covers compositions and methods for the transient delivery of nucleases. This innovation relates to the use of recombinant adeno-associated viruses (rAAV) that have nucleases grafted onto capsid proteins. Solutions proposed in this patent address challenges linked to prolonged expression of gene editing systems, which can lead to genotoxicity. Wang explores alternative methods such as the delivery of mRNA or proteins to mitigate off-target effects in gene editing.
Career Highlights
Dan Wang’s career is marked by his dedication to advancing gene therapy techniques. He works at the University of Massachusetts, where his research focuses on innovative biotechnological solutions. His expertise has led him to develop effective gene editing methods that prioritize safety and efficacy in therapeutic applications.
Collaborations
Wang's work has benefitted from collaborations with esteemed colleagues, including Guangping Gao and Phillip D. Zamore. Together, they are exploring new frontiers in gene therapeutics, combining their expertise to tackle complex biological problems and enhance treatment outcomes.
Conclusion
In summary, Dan Wang's contributions to the field of gene therapeutics are significant and far-reaching. With five patents to his credit, his innovative approaches to treating bone disorders highlight the potential for transformative therapies in gene editing and modulation. As he continues to collaborate with other experts, the future looks promising, with the potential for groundbreaking advancements that could impact countless lives.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.