Dale E Muzzey

Title: Innovations in Noninvasive Prenatal Screening by Dale E. Muzzey

Introduction

Dale E. Muzzey is a prominent inventor based in San Francisco, CA, known for her significant contributions to the field of prenatal screening. With a total of two patents, her work focuses on advancing noninvasive methods for detecting chromosomal abnormalities in fetuses.

Latest Patents

Dale E. Muzzey's latest patents include innovative methods for noninvasive prenatal screening. The first patent, titled "Noninvasive prenatal screening using dynamic iterative depth optimization with depth-scaled variance determination," describes techniques for analyzing fetal and maternal cell-free DNA to identify chromosomal abnormalities such as aneuploidy or microdeletions. This method involves measuring the dosage of a test chromosome and determining statistical significance based on sequencing reads from maternal samples. The second patent, "Noninvasive prenatal screening using dynamic iterative depth optimization," similarly focuses on analyzing fetal cell-free DNA to assess chromosomal abnormalities. This patent emphasizes measuring the fetal fraction of cell-free DNA and determining the likelihood of abnormalities based on the measured dosage and expected values.

Career Highlights

Dale E. Muzzey is currently associated with Myriad Women's Health, Inc., where she continues to innovate in the field of prenatal diagnostics. Her work has the potential to significantly improve prenatal care and outcomes for expectant mothers.

Collaborations

Dale collaborates with notable colleagues, including Kevin R. Haas and Jeffrey R. Tratner, who contribute to her research and development efforts in the field.

Conclusion

Dale E. Muzzey's contributions to noninvasive prenatal screening represent a significant advancement in maternal-fetal medicine. Her innovative patents pave the way for improved diagnostic methods that can enhance prenatal care for women.