Dae Kee Kwon

Title: **The Innovations of Dae Kee Kwon: Pioneering Transgenic Pig Research**

Introduction

Dae Kee Kwon is a notable inventor based in Seoul, South Korea, recognized for his pioneering work in the field of genetic engineering, particularly in the development of transgenic pigs. With a focus on innovations that have significant implications for organ transplantation and immunology, Kwon has made substantial contributions to the scientific community.

Latest Patents

Dae Kee Kwon holds two patents that highlight his innovative approaches. The first patent details a transgenic pig that expresses sTNFR1-Fc genes, which introduces a gene encoding for a fusion protein that can suppress immune and inflammatory responses by secreting an inhibitory substance that dampens TNF-α activity in the blood. This transgenic pig model can be effectively utilized for xenograft procedures and presents a significant advantage through its O blood type, allowing for universal compatibility in transplants.

The second patent relates to a method for producing a transgenic pig that simultaneously expresses human HO-1 genes and TNFR1-Fc fusion genes. This invention aims to inhibit immune rejection responses in organ transplantation, providing a novel solution to rejection issues commonly faced in xenotransplantation. The patent also encompasses a somatic-cell donor cell line for creating these transgenic pigs and methods for producing usable organs.

Career Highlights

Kwon's career includes key positions at Hanwha Advanced Materials Corporation and the Snur & Db Foundation. His leadership and innovative thinking have played vital roles in advancing research and commercial applications in genetic engineering and biotechnology.

Collaborations

Throughout his career, Kwon has collaborated with numerous talented individuals, including his coworkers Curie Ahn and Byeong Chun Lee. These collaborations have fostered a dynamic research environment that encourages innovative solutions to complex problems in organ transplantation and immune response suppression.

Conclusion

Dae Kee Kwon's innovative contributions to the field of genetic engineering and his patents on transgenic pigs represent significant advancements in medical science. His work not only enhances our understanding of immunology but also opens new avenues for improving organ transplantation methodologies. Kwon’s commitment to innovation continues to inspire future research and development in biotechnology.