Company Filing History:
Years Active: 2001-2007
Title: Innovations by Cynthia B. Curty: Pioneering Research in Acyclic Nucleoside Derivatives
Introduction
Cynthia B. Curty, based in Gurnee, IL, is a notable inventor in the field of medicinal chemistry, contributing significantly to the synthesis of acyclic nucleoside derivatives. With two patents to her name, Curty has made considerable advancements in antiviral drug development, exemplifying her expertise and innovative approach in this pivotal area of research.
Latest Patents
Curty’s latest patents focus on the synthesis of acyclic nucleoside derivatives. One of her prominent innovations details a novel process for synthesizing the antiviral valomaciclovir stearate. This process involves reducing an esterified guanine acetal to the corresponding alcohol, followed by a reaction with an activated amino acid and subsequent N-deprotection. Notably, the method emphasizes the preparation of the esterified guanine acetal from a 9-guanine derivative, featuring an acyclic hydroxymethylbutylacetal. Furthermore, these processes are designed to be adaptable to one-pot reactions, enhancing efficiency and simplifying the synthesis process.
Career Highlights
Over her career, Curty has worked with companies such as Medivir AB, where she has contributed her expertise in the field of nucleoside chemistry. Her work has been influential in driving forward research that has implications for antiviral therapies, demonstrating her significant impact in pharmaceutical research and development.
Collaborations
Throughout her professional journey, Curty has collaborated with notable colleagues, including M. Robert Leanna and Steven M. Hannick. These collaborations have facilitated the advancement of her research, allowing for a synergistic approach to tackling complex challenges in drug synthesis and development.
Conclusion
Cynthia B. Curty is an accomplished inventor whose work on acyclic nucleoside derivatives has paved the way for advancements in antiviral treatments. Her innovative methods and collaborative spirit underscore her vital role in the scientific community, particularly in the ongoing search for effective therapeutic solutions.