This inventor holds 5 USPTO granted patents. Top assignees: Case Western Reserve University, The Cleveland Clinic Foundation. Active years: 2021-2026.
Location History:
- Cleveland, OH (US) (2021)
- Bogota, CO (2022)
Company Filing History:
5 out of 1,361 
2 out of 1,071 
Years Active: 2021-2026
Title: Cristian Barrera: Innovator in Cancer Research
Introduction
Cristian Barrera is a notable inventor based in Cleveland, OH, who has made significant contributions to the field of cancer research. He holds a total of 5 patents that focus on innovative methods for predicting cancer recurrence and response to immunotherapy. His work is instrumental in advancing the understanding of tumor biology and improving patient outcomes.
Latest Patents
One of Cristian's latest patents is titled "Phenotyping tumor infiltrating lymphocytes on hematoxylin and eosin (HandE) stained tissue images to predict recurrence in lung cancer." This invention involves a sophisticated process where a processor accesses an image of cancerous tissue, segments cellular nuclei, and classifies them as lymphocytes or non-lymphocytes. The technology computes a frequency distribution of clustered lymphocytes and utilizes a machine learning classifier to predict the likelihood of cancer recurrence.
Another significant patent is "Predicting response to immunotherapy using computer extracted features of cancer nuclei from hematoxylin and eosin (HandE) stained images of non-small cell lung cancer (NSCLC)." This invention focuses on analyzing digitized images of NSCLC tissue, extracting nuclear radiomic features, and generating a nuclear cell graph. The resulting data is then used to classify the tissue as a responder or non-responder to immunotherapy, providing valuable insights for treatment planning.
Career Highlights
Cristian Barrera has worked with prestigious institutions such as Case Western Reserve University and The Cleveland Clinic Foundation. His experience in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Cristian has collaborated with notable colleagues, including Anant Madabhushi and Xiangxue Wang. Their combined expertise has further enhanced the impact of Cristian's research and innovations in cancer diagnostics.
Conclusion
Cristian Barrera is a pioneering inventor whose work in cancer research is shaping the future of medical diagnostics and treatment. His patents reflect a commitment to improving patient care through innovative technology.