Oregon, WI, United States of America

Craig E Smith

USPTO Granted Patents = 12 

 


Average Co-Inventor Count = 4.3

ph-index = 10

Forward Citations = 630(Granted Patents)


Company Filing History:


Years Active: 1999-2009

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12 patents (USPTO):Explore Patents

Title: Craig E. Smith: Innovator in Biomolecular Detection and Cell Concentration

Introduction

Craig E. Smith is a notable inventor based in Oregon, Wisconsin, recognized for his contributions to the fields of biomolecular detection and cell concentration. With a total of 12 patents to his name, Smith has developed innovative methods that enhance the efficiency and effectiveness of biological research.

Latest Patents

Among his latest patents, one significant invention is the method for the direct detection of biomolecules in a gel. This technique allows for the detection of a target biomolecule directly in a polyacrylamide gel, where it has been separated from other substances. The process involves immersing the gel in a water-miscible aqueous extracting medium containing a base, which shrinks the gel by at least ten percent. Following this, the gel is washed with water to restore it to its original size.

Another important patent focuses on cell concentration and lysate clearance using paramagnetic particles. This method provides techniques for concentrating or harvesting cells and clearing solutions of disrupted biological material, such as cell lysates or mammalian tissue homogenates. Additionally, it includes methods for isolating target nucleic acids, such as RNA or DNA, from cleared solutions, making them suitable for immediate downstream processing without further purification.

Career Highlights

Throughout his career, Craig E. Smith has worked with prominent companies in the biotechnology sector, including Promega Corporation and Pierce Biotechnology, Inc. His work in these organizations has significantly contributed to advancements in molecular biology techniques.

Collaborations

Smith has collaborated with notable colleagues, including Rex M. Bitner and Josephine C. Grosch, further enhancing the impact of his innovations in the field.

Conclusion

Craig E. Smith's innovative approaches to biomolecular detection and cell concentration have made a lasting impact on the biotechnology industry. His patents reflect a commitment to advancing scientific research and improving methodologies in biological applications.

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