Location History:
- Slough, GB (2020 - 2022)
- London, GB (2022 - 2023)
Company Filing History:
Years Active: 2020-2025
Title: Colin Mark Jaques: Innovator in Bioprocess Control
Introduction
Colin Mark Jaques is a notable inventor based in Slough, GB. He has made significant contributions to the field of bioprocessing, particularly through his innovative patents. With a total of 5 patents to his name, Jaques has established himself as a key figure in the development of automated control systems for cell culture.
Latest Patents
One of Jaques' latest patents focuses on the automated control of cell culture using Raman spectroscopy. This invention enhances the monitoring and control of bioprocesses by generating generic calibration models that are independent of cell lines. The technology utilizes inline Raman probes to monitor critical parameters such as glucose, lactate, glutamate, ammonium, viable cell concentration (VCC), total cell concentration (TCC), and product concentration. The calibration models were developed using two different CHOK1SV GS-KO™ cell lines that produce distinct monoclonal antibodies (mAbs). The predictive models created were validated with an independent CHOK1SV GS-KO™ cell line, demonstrating minor prediction errors throughout the cell culture process. This advancement allows for the application of spectroscopic Process Analytical Technology (PAT) techniques in clinical manufacturing environments, where processes are typically executed once or twice based on a common platform.
Career Highlights
Colin Mark Jaques is currently employed at Lonza Inc., a leading company in the life sciences sector. His work focuses on improving bioprocessing techniques, which are crucial for the production of biopharmaceuticals. His innovative approaches have contributed to the efficiency and reliability of bioprocesses in the industry.
Collaborations
Jaques has collaborated with several professionals in his field, including Mohsan Waseem Khan and Rita D'Ornelas P De Barros Costa. These collaborations have further enhanced the development and application of his innovative technologies.
Conclusion
Colin Mark Jaques is a prominent inventor whose work in bioprocess control has made a significant impact on the industry. His innovative patents and contributions to automated cell culture monitoring demonstrate his commitment to advancing biopharmaceutical production.