Location History:
- Chapel Hill, NC (US) (2003)
- Rockville, MD (US) (2013)
- San Diego, CA (US) (2020)
Company Filing History:
1 out of 78 
1 out of 12 
1 out of 832,880 Years Active: 2003-2020
Title: Clyde A Hutchison, III: Innovator in Nucleic Acid Technologies
Introduction
Clyde A Hutchison, III is a prominent inventor based in San Diego, CA. He has made significant contributions to the field of nucleic acid technologies, holding a total of 3 patents. His work focuses on encoding human-readable text into nucleic acid sequences and methods for amplifying DNA molecules.
Latest Patents
One of Hutchison's latest patents involves methods and apparatus for encoding human-readable text into nucleic acid sequences. This innovation allows for the encoding of non-genetic messages with a reduced probability of biological impact. The process includes mapping symbols to codon identifiers, ensuring that each symbol does not correspond to a codon that generates an amino acid residue equivalent to the respective symbol. Additionally, he has developed synthetic nucleic acid sequences that comprise such human-readable text, along with methods for identifying cells or organisms containing these sequences.
Another notable patent focuses on amplifying single-stranded circular DNA molecules using a rolling circle amplification method. This technique allows for the amplification of a small number of DNA copies, achieving a degree of amplification of about 10^9 fold or higher. The method can also be utilized for cell-free cloning of DNA, showcasing Hutchison's innovative approach to DNA technology.
Career Highlights
Clyde A Hutchison, III has worked with notable companies in the biotechnology sector, including Synthetic Genomics, Inc. and Codex DNA, Inc. His experience in these organizations has contributed to his expertise in nucleic acid technologies and innovation.
Collaborations
Throughout his career, Hutchison has collaborated with esteemed colleagues such as Hamilton O Smith and Michael G Montague. These partnerships have furthered his research and development efforts in the field.
Conclusion
Clyde A Hutchison, III is a distinguished inventor whose work in nucleic acid technologies has paved the way for advancements in encoding and amplifying DNA. His contributions continue to influence the biotechnology landscape, demonstrating the importance of innovation in this field.