Clarke E Slemon

Title: Clarke E Slemon: Innovator in Electrochemical Processes and Pharmaceuticals

Introduction

Clarke E Slemon is a notable inventor based in Toronto, Canada. He has made significant contributions to the fields of electrochemistry and pharmaceuticals, holding two patents that showcase his innovative approaches to chemical processes.

Latest Patents

Slemon's latest patents include a process for the electrochemical reduction of 7-ketolithocholic acid to ursodeoxycholic acid. This process can be conducted alone or alongside a simultaneous electrochemical oxidation of chenodeoxycholic acid to 7-ketolithocholic acid. The patents also disclose solvents that promote stereoselectivity to ursodeoxycholic acid during the electrochemical reaction. Another significant patent involves a process for preparing ampicillin trihydrate. This process includes acylating silylated 6-aminopenicillanic acid with D(-)-α-phenylglycylchloride hydrochloride directly in the silylation reaction mixture, using urea as an acid acceptor, followed by hydrolyzing the reaction product and precipitating ampicillin trihydrate from the resulting aqueous solution.

Career Highlights

Throughout his career, Clarke E Slemon has worked with various companies, including Canada Packers Inc. and Slemon, Clarke E. His work has significantly impacted the pharmaceutical industry, particularly in the development of processes that enhance the efficiency and purity of drug production.

Collaborations

Slemon has collaborated with notable individuals in his field, including Kekhusroo R Bharucha and Heinrich Maria Schrenk. These collaborations have contributed to the advancement of his research and the successful development of his patented processes.

Conclusion

Clarke E Slemon's innovative work in electrochemical processes and pharmaceuticals has led to significant advancements in these fields. His patents reflect a commitment to improving chemical processes and drug production, showcasing his role as a key inventor in the industry.