Chuanyang Shang

Title: Innovations of Chuanyang Shang in Biochemical Engineering

Introduction

Chuanyang Shang is a prominent inventor based in Ningbo, China, known for his significant contributions to the field of biochemical engineering. He has been instrumental in developing innovative polypeptides that enhance the synthesis of chiral compounds, which are crucial in various industrial applications. With a total of two patents to his name, his work is paving the way for more efficient and environmentally friendly production processes.

Latest Patents

Chuanyang Shang's latest patents include "Engineered ketoreductase polypeptides and uses thereof" and "Engineered transaminase polypeptides and uses thereof." The first patent provides amino acid sequences of ketoreductase polypeptides that are useful for asymmetrically synthesizing chiral alcohol compounds. It details the preparation process and reaction conditions relevant to industrial applications. The engineered ketoreductase polypeptides exhibit superior catalytic activity and thermal stability compared to other enzymes, facilitating enzyme purification through heat treatment. This innovation simplifies the production process of chiral alcohol compounds, reduces production costs, and minimizes environmental impact.

The second patent focuses on engineered transaminase polypeptides, which are also designed for the asymmetric synthesis of chiral amine compounds. This patent outlines the amino acid sequences and preparation processes, highlighting the engineered polypeptides' enhanced catalytic activity and stability. Notably, these polypeptides are not inhibited by chiral amine products during synthesis, resulting in higher unit activity and promising industrial application prospects.

Career Highlights

Chuanyang Shang is currently associated with Enzymaster Bio-engineering Co., Ltd., where he continues to innovate in the field of enzyme engineering. His work has garnered attention for its potential to revolutionize the production of chiral compounds, making processes more efficient and sustainable.

Collaborations

He collaborates with notable colleagues, including Haibin Chen and Yong Koy Bong, who contribute to the advancement of his research and innovations.

Conclusion

Chuanyang Shang's contributions to biochemical engineering through his patented innovations are setting new standards in the synthesis of chiral compounds. His work not only enhances industrial processes but also promotes environmental sustainability.