Company Filing History:
Years Active: 2005-2009
Title: Chuan Li: Innovator in Nucleic Acid Amplification Technologies
Introduction
Chuan Li is a prominent inventor based in St. Louis, MO (US). He has made significant contributions to the field of molecular biology, particularly in the area of nucleic acid amplification. With a total of 2 patents, his work has advanced the methodologies used in genetic research and diagnostics.
Latest Patents
Chuan Li's latest patents focus on innovative processes for directionally ligating double-stranded nucleic acids. One of his notable inventions involves amplification mixtures, kits, and processes designed for amplifying nucleic acids. These processes utilize an amplification mixture that includes a polymerase, a deoxynucleotidetriphosphate (dNTP) mixture containing modified dNTPs, and both a first and second primer. His inventions also provide dNTP mixtures that contain modified nucleotides, which, when incorporated into a polynucleotide, offer resistance to enzymatic degradation by exonucleases at the sites of incorporation. Additionally, the patents cover the amplicons and vectors that incorporate these modified nucleotides.
Career Highlights
Chuan Li is currently employed at Sigma-Aldrich Co. LLC, where he continues to develop innovative solutions in the field of biotechnology. His work has been instrumental in enhancing the efficiency and reliability of nucleic acid amplification techniques.
Collaborations
Chuan has collaborated with notable colleagues, including Brian W. Ward and Keming Song, to further advance the research and development of nucleic acid technologies.
Conclusion
Chuan Li's contributions to nucleic acid amplification technologies have positioned him as a key figure in the field of molecular biology. His innovative patents and ongoing work at Sigma-Aldrich Co. LLC continue to impact genetic research and diagnostics significantly.