Company Filing History:
Years Active: 2014
Title: Christopher Wahl: Innovating the Crystallization of Lamivudine
Introduction
Christopher Wahl, an accomplished inventor based in Philadelphia, PA, has made significant contributions to the field of pharmaceuticals through his innovative work. With a focus on improving the crystallization process of lamivudine, he holds a valuable patent that enhances the efficiency and stability of this important compound.
Latest Patents
Wahl's patent, titled "Preparation of Lamivudine Form I," describes a thermodynamically controlled process for preparing Form I polymorph of lamivudine. This patent outlines a method involving the crystallization of Form I at temperatures ranging from about 0° C. to about 50° C. The process consists of a mixture that includes lamivudine or its acid salt, a solvent system comprising water and at least one organic solvent, and optionally, Form I seed. Particularly innovative is that when a lamivudine acid salt is utilized, the crystallizing step is performed in the presence of a base, ensuring that the water activity of the solvent system is maintained in a range that allows for the stabilization of Form I as the most thermodynamically favorable form.
Career Highlights
Wahl's career at Merck Sharp & Dohme Corporation has been marked by his dedication to pharmaceutical research and development. Through his work, he has demonstrated an advanced understanding of crystallization techniques and their applications in drug formulation, positioning himself as a notable figure within his field.
Collaborations
Throughout his career, Wahl has collaborated with various esteemed colleagues, including Benjamin M Cohen and Itzia Arroyo. This cooperative spirit has fostered an environment of innovation and creativity, driving advancements in pharmaceutical technologies and product development.
Conclusion
Christopher Wahl's contributions to the field of pharmaceutical science, particularly through his patent for the crystallization of lamivudine, exemplify the essential role inventors play in enhancing drug stability and efficacy. His ongoing work continues to influence the industry and paves the way for future innovations in pharmaceutical formulations.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.