Christopher S Navara

Title: Christopher S Navara: Innovator in Stem Cell Research

Introduction

Christopher S Navara is a notable inventor based in San Antonio, TX (US). He has made significant contributions to the field of stem cell research, particularly through his innovative patent that focuses on mitochondrial inhibitors.

Latest Patents

Navara holds a patent titled "Mitochondrial inhibitors for use in culturing pluripotent stem cells." This patent discloses certain heterocyclic organic compounds that inhibit mitochondrial respiration while maintaining the pluripotency of human embryonic stem cells in culture, even in the presence of oxygen. The patent exemplifies compounds such as substituted 5-aminotetrazoles, which act as reversible mitochondrial inhibitors. The pluripotency of the stem cells after culture is verified by the overexpression of pluripotent stem cell markers, including genes like NANOG, OCT4, and SURVIVIN after periods of culture in ambient oxygen. Navara's work in this area has the potential to advance stem cell therapies and regenerative medicine.

Career Highlights

Throughout his career, Navara has been associated with prestigious institutions such as Leland Stanford Junior University and the University of Texas System. His work has garnered attention for its innovative approach to enhancing stem cell culture techniques.

Collaborations

Navara has collaborated with notable colleagues, including David Alvin Tyvoll and James P Collman. These collaborations have contributed to the advancement of research in the field of stem cell biology.

Conclusion

Christopher S Navara is a pioneering inventor whose work in mitochondrial inhibitors has the potential to transform stem cell research and applications. His contributions are significant in the ongoing quest for advancements in regenerative medicine.