The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jun. 19, 2015
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Board of Regents of the University of Texas System, Austin, TX (US);
David Alvin Tyvoll, La Jolla, CA (US);
Christopher S. Navara, San Antonio, TX (US);
James P. Collman, Stanford, CA (US);
Christopher Jeffrey Barile, San Carlos, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Board of Regents of the University of Texas System, Austin, TX (US);
Abstract
Disclosed are certain heterocyclic organic compounds that inhibit mitochondrial respiration and also lead to the maintenance of pluripotency of human embryonic stem cells in culture, even in the presence of oxygen. Exemplified are compounds, such as substituted 5-aminotetrazoles, which are reversible mitochondrial inhibitors. The pluripotency of the stem cells after culture is verified by the overexpression of pluripotent stem cell markers, exemplified by at least one of the genes NANOG, OCT4, and SURVIVIN after periods of culture in ambient oxygen.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile