Christopher J Apolito

Title: **Christopher J. Apolito: Innovator in Nuclear Receptor Research**

Introduction

Christopher J. Apolito, based in Durham, North Carolina, is a notable inventor with expertise in the field of nuclear receptor research. With a keen focus on scientific innovation, he has contributed significantly through his patented work, showcasing his dedication to enhancing our understanding of receptor biology.

Latest Patents

Christopher holds a patent titled "Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same." This innovative patent outlines a method for modifying a test nuclear receptor (NR) polypeptide. The method involves aligning the test NR polypeptide sequence with one or more reference NR polypeptide sequences that have known X-ray structures. By creating a three-dimensional model based on these coordinates and examining characteristic differences, his approach enables the mutation of specific amino acid residues in the test NR polypeptide, leading to significant modifications.

Career Highlights

Throughout his career, Christopher has worked at SmithKline Beecham Corporation, where he has applied his expertise in nuclear receptor research to advance scientific understanding in the field. His contributions have not only furthered his career but have also had a positive impact on the broader scientific community.

Collaborations

Christopher has collaborated with esteemed colleagues including Randy K. Bledsoe and Millard Hurst Lambert, III. These partnerships have enriched his research endeavors and promoted a collaborative environment aimed at innovative discovery and development.

Conclusion

With a strong commitment to research and a significant patent to his name, Christopher J. Apolito exemplifies the spirit of innovation in the realm of nuclear receptor biology. His work stands as a testament to the impact that dedicated inventors can have on science and medicine.