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For the Inventor, By the Inventor

North Liberty, IA, United States of America

Christopher Anthony Vakulskas

This inventor holds 20 USPTO granted patents and 31 published patent applications, primarily in CRISPR Technology. Top assignee: Integrated Dna Technologies, Inc.. Active years: 2020-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Christopher Anthony Vakulskas. Retrieved from https://idiyas.com/inventor/christopher-anthony-vakulskas

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank
USPTO Granted Patents = 20 

% Patents Active = 100.0

Average Co-Inventor Count = 3.3

ph-index = 2

Forward Citations = 19(Granted Patents)


Company Filing History:

goldMedal20 out of 111 
 
Integrated Dna Technologies, Inc.
 patents

Years Active: 2020-2026

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Areas of Expertise:
CRISPR
Cas9
Reverse Transcriptase
Mutants
DNA Cleavage
Thermostability
Protein Fusions
Gene Editing
Polypeptides
53BP1 Binding
AAV
CPF1
20 patents (USPTO):Explore Patents
1. 12741995 - UBIQUITIN VARIANT WITH HIGH AFFINITY FOR BINDING 53BP1 REDUCES THE AMOUNT OF AAV NEEDED TO ACHIEVE HIGH RATES OF HDR (2026-09-22),
2. 12723264 - S PYOGENES CAS9 MUTANT GENES AND POLYPEPTIDES ENCODED BY SAME (2026-09-01),
3. 12618054 - CRISPR/CPF1 SYSTEMS AND METHODS (2026-05-05),
4. 12559734 - Reverse Transcriptase Mutants with Increased Activity and Thermostability (2026-02-24),
5. 12454684 - Methods using novel CPF1 mutations that enhance the DNA cleavage activity ofsp. CPF1 (2025-10-28),
6. 12435324 - sp. Cas12a mutants with enhanced cleavage activity at non-canonical TTTT protospacer adjacent motifs (2025-10-07),
7. 12435318 - Reverse transcriptase mutants with increased activity and thermostability (2025-10-07),
8. 12351799 - S. pyogenes CAS9 mutant genes and polypeptides encoded by same (2025-07-08),
9. 12297435 - Mutations inCas9 discovered by broad scanning mutagenesis demonstrate enhancement of DNA cleavage activity (2025-05-13),
10. 12264342 - ND2006 CAS12A mutant genes and polypeptides encoded by same (2025-04-01),
11. 12168765 - CAS9 mutant genes and polypeptides encoded by same (2024-12-17),
12. 12152258 - Optimized protein fusions and linkers (2024-11-26),
13. 12012433 - Expression and purification of Cas enzymes (2024-06-18),
14. 11999979 - sp. CAS12A mutants with enhanced cleavage activity at non-canonical TTTT protospacer adjacent motifs (2024-06-04),
15. 11913014 - Cas9 mutant genes and polypeptides encoded by same (2024-02-27),

Title: The Innovations of Christopher Anthony Vakulskas

Introduction

Christopher Anthony Vakulskas is a prominent inventor based in North Liberty, IA (US). He has made significant contributions to the field of biotechnology, holding a total of 15 patents. His work primarily focuses on enhancing DNA cleavage activities and improving reverse transcriptase functionality.

Latest Patents

Among his latest patents is the development of Cas12a mutants with enhanced cleavage activity at non-canonical TTTT protospacer adjacent motifs. This patent describes CAS12A mutants derived from Lachnospiraceae bacterium, which exhibit improved DNA cleavage activities compared to the wild-type enzyme. Another notable patent involves reverse transcriptase mutants with increased activity and thermostability. This disclosure provides insights into Moloney murine leukemia virus (MMLV) reverse transcriptase mutants, detailing suitable amino acid positions for mutagenesis and methods for synthesizing cDNA from RNA templates.

Career Highlights

Christopher is currently employed at Integrated DNA Technologies, Inc., where he continues to innovate and develop new biotechnological solutions. His work has had a profound impact on the field, particularly in the areas of genetic engineering and molecular biology.

Collaborations

He has collaborated with notable colleagues, including Michael Allen Collingwood and Mark Aaron Behlke, contributing to a dynamic research environment that fosters innovation.

Conclusion

Christopher Anthony Vakulskas exemplifies the spirit of innovation in biotechnology through his extensive patent portfolio and collaborative efforts. His contributions are paving the way for advancements in genetic research and applications.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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