Location History:
- Princeton, NJ (US) (2010)
- New York, NY (US) (2014 - 2016)
Company Filing History:
Years Active: 2010-2016
Title: Christoph Schaniel: Innovator in Cellular Engineering
Introduction
Christoph Schaniel is a prominent inventor based in New York, NY (US), known for his groundbreaking work in the field of cellular engineering. With a total of 3 patents, Schaniel has made significant contributions to the understanding and manipulation of mammalian cells, particularly in the context of stem cell differentiation.
Latest Patents
One of Schaniel's latest patents is titled "Engineered cellular pathways for programmed autoregulation of differentiation." This invention provides compositions and methods for programming mammalian cells to perform desired functions. Specifically, it focuses on programming stem cells to differentiate into a desired cell type. The invention introduces quorum sensing systems that regulate the expression of cell fate regulators in mammalian host cells, such as stem cells. These systems comprise vectors that express components of a bacterial quorum sensing pathway, including proteins that catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer. Additionally, the vectors link genes encoding cell fate regulators to a promoter induced by the autoinducer/regulatory partner complex. The system can also include vectors in which genes encoding additional cell fate regulators are operably linked to a promoter induced by a factor synthesized in response to a first stage of differentiation, thereby triggering a second stage of differentiation.
Career Highlights
Schaniel's career is marked by his innovative research and contributions to the field of cellular biology. His work has been instrumental in advancing the understanding of how to control cell differentiation, which has significant implications for regenerative medicine and therapeutic applications.
Collaborations
Throughout his career, Schaniel has collaborated with notable colleagues, including Ihor R. Lemischka and Ron Weiss. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Christoph Schaniel is a leading figure in the field of cellular engineering, with a focus on programming stem cells for specific functions. His innovative patents and collaborative efforts continue to push the boundaries of what is possible in cellular biology.