La Jolla, CA, United States of America

Christine Esau

USPTO Granted Patents = 14 

 

 

Average Co-Inventor Count = 4.1

ph-index = 5

Forward Citations = 244(Granted Patents)


Company Filing History:


Years Active: 2010-2019

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14 patents (USPTO):Explore Patents

Title: Christine Esau: Pioneering Innovations in MicroRNA Therapeutics

Introduction

Christine Esau, a remarkable inventor located in La Jolla, California, has made significant contributions to the field of biomedicine with her innovative research and discoveries. With an impressive portfolio of 14 patents, she has focused primarily on the targeting of microRNAs for therapeutic applications, particularly in the treatment of liver cancer and cardiovascular diseases.

Latest Patents

Among Christine Esau’s latest patents is a groundbreaking method for targeting microRNAs for the treatment of liver cancer. This invention encompasses the administration of a compound comprising a modified oligonucleotide, specifically designed to target certain miRNAs associated with liver cancer. The patents detail compositions that may include these modified oligonucleotides, which have shown efficacy in inhibiting cell proliferation and inducing apoptosis in hepatocellular carcinoma cells. Another notable patent involves methods for modulating miR-122A, aimed at addressing cardiovascular or metabolic diseases characterized by elevated cholesterol levels. This invention highlights the potential of oligomeric compounds to enhance the therapeutic landscape for managing liver tissue triglyceride accumulation through strategic modulation of miR-122A.

Career Highlights

Throughout her career, Christine has worked with renowned companies including Regulus Therapeutics Inc. and Rosetta Genomics Ltd. Her research within these organizations has propelled advancements in the understanding and application of microRNA therapeutics, establishing her as a leader in the field of molecular medicine. The impact of her work is reflected in her impressive patent portfolio, which serves as a testament to her innovative spirit and commitment to medical advancement.

Collaborations

Christine has collaborated with notable colleagues, including C Frank Bennett and Eric G Marcusson. These partnerships have further enriched her research endeavors, allowing her to expand her knowledge and influence in the realms of molecular biology and therapeutic innovations. The collaboration with peers has not only enhanced her inventions but has also contributed to the broader scientific community.

Conclusion

In conclusion, Christine Esau stands out as a pioneering inventor whose work has significantly impacted the field of therapeutics. Her dedication to exploring the intricacies of microRNA biology has opened new avenues for treatment options in life-threatening diseases. With her 14 patents and collaborative spirit, Christine continues to inspire and contribute to the advancement of medical science.

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