The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2012
Filed:
Jan. 27, 2007
Christine Esau, La Jolla, CA (US);
Eric E. Swayze, Carlsbad, CA (US);
Balkrishen Bhat, Carlsbad, CA (US);
Garth A. Kinberger, San Diego, CA (US);
Christine Esau, La Jolla, CA (US);
Eric E. Swayze, Carlsbad, CA (US);
Balkrishen Bhat, Carlsbad, CA (US);
Garth A. Kinberger, San Diego, CA (US);
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Compounds, compositions and methods are provided for modulating the levels expression, processing and function of miRNAs. The compositions comprise oligomeric compounds targeted to small non-coding RNAs and miRNAs. The oligomeric compounds possess potent miRNA inhibitory activity, and further exhibit improved therapeutic index. Further provided are methods for selectively modulating miRNA activity in a cell.