Inventors with similar research interests:
Location History:
- San Deigo, CA (US) (2016)
- San Diego, CA (US) (2014 - 2017)
- Cambridge, MA (US) (2016 - 2021)
- Carlsbad, CA (US) (1998 - 2022)
Company Filing History:
40 out of 1,035 
27 out of 61 
6 out of 271 
Years Active: 1998-2025
Areas of Expertise:
Title: The Innovative Contributions of Balkrishen Bhat in Nucleic Acid Delivery
Introduction: Balkrishen Bhat, a renowned inventor based in Carlsbad, California, has made significant contributions in the field of synthetic nucleic acids. With an impressive portfolio of 78 patents, his work primarily focuses on innovative methods and compositions that enhance the delivery of nucleic acids to cells and tissues.
Latest Patents: Among his latest patents, two stand out due to their potential implications in therapeutic applications. The first patent outlines "Compositions and methods for facilitating delivery of synthetic nucleic acids to cells," wherein he provides innovative solutions using targeting moiety-conjugated oligonucleotides, such as N-acetylgalactosamine (GalNAc), to improve delivery efficiency. The second patent relates to "Nucleic acid conjugates and uses thereof," which describes conjugates that include targeting moieties like sugars, folates, and cell-penetrating peptides for more effective delivery of nucleic acids and other agents. These inventions also cover methods for treating or preventing diseases, modulating gene expression, and include the development of related kits.
Career Highlights: Balkrishen Bhat has held influential roles in leading biotechnology firms, most notably at Isis Pharmaceuticals, Inc. and Regulus Therapeutics Inc. His work at these companies has been integral in shaping innovative approaches to gene therapy and nucleic acid delivery systems.
Collaborations: Throughout his career, Bhat has collaborated with notable colleagues including Eric E Swayze and Thazha P Prakash. These partnerships have further enriched his research and contributed to the advancement of technologies that facilitate nucleic acid delivery.
Conclusion: With 78 patents to his name, Balkrishen Bhat continues to push the boundaries of science and technology in synthetic nucleic acid delivery. His innovative compositions and methods not only promise enhanced therapeutic strategies but also signify important progress in the realm of genetic research and medicine. As he continues to collaborate with other leading experts in the field, the future is bright for advancements arising from his work.