Christina Kantzow

Title: Christina Kantzow: Innovator in Biochemical Engineering

Introduction

Christina Kantzow is a prominent inventor based in Munich, Germany. She has made significant contributions to the field of biochemical engineering, particularly in the development of enzyme mutants for pharmaceutical applications. With a total of two patents to her name, her work is paving the way for advancements in the synthesis of important compounds.

Latest Patents

Christina's latest patents include innovations related to 7β-hydroxysteroid dehydrogenase mutants and processes for the preparation of ursodeoxycholic acid. The first patent provides a nucleic acid molecule that encodes a 7β-hydroxysteroid dehydrogenase (7β-HSDH) mutant. This mutant is designed to catalyze the stereospecific enzymatic reduction of a 7-ketosteroid to the corresponding 7-hydroxysteroid. Notably, the mutant exhibits decreased substrate inhibition and altered cofactor usage compared to the wildtype 7β-HSDH. The second patent focuses on novel 7β-hydroxysteroid dehydrogenase mutants and their use in enzymatic reactions of cholic acid compounds, particularly in the preparation of ursodeoxycholic acid (UDCS). This invention also details processes for synthesizing UDCS using recombinant, multiply-modified microorganisms.

Career Highlights

Christina Kantzow is currently employed at Pharmazell GmbH, where she continues to innovate in the field of biochemistry. Her work has garnered attention for its potential applications in the pharmaceutical industry, particularly in the development of treatments that utilize her patented enzyme mutants.

Collaborations

Throughout her career, Christina has collaborated with notable colleagues, including Dirk Weuster-Botz and Michael Braun. These partnerships have enhanced her research and contributed to the successful development of her patented technologies.

Conclusion

Christina Kantzow is a trailblazer in biochemical engineering, with her innovative patents significantly impacting the pharmaceutical landscape. Her work exemplifies the importance of research and collaboration in advancing scientific knowledge and applications.