Location History:
- Merzhausen, DE (2012)
- Ehrenkirchen, DE (2013 - 2015)
Company Filing History:
Years Active: 2012-2015
Title: Inventor Christian Scheckermann: Advancements in Sialyltransferase and G-CSF Production
Introduction
Christian Scheckermann, based in Ehrenkirchen, Germany, is a distinguished inventor renowned for his significant contributions to biotechnology. With a total of four patents to his name, his work primarily focuses on innovative methods in the production and purification of essential proteins, showcasing the intersection of science and innovation.
Latest Patents
One of Scheckermann's notable inventions is a method of producing and purifying an active soluble sialyltransferase. This patent details a process for generating the N-Acetylgalactosamine (Gal NAc)-α-2,6-sialyltransferase I (ST6GalNAcI) polypeptide using Chinese Hamster Ovary (CHO) cells. The purification method involves a combination of chromatography steps, resulting in a high yield of a highly pure and active sialyltransferase. The ST6GalNAcI produced can be utilized for glycosylating therapeutic proteins, including Granulocyte Colony-Stimulating Factor (G-CSF).
Another critical patent relates to the acquisition of biologically active recombinant human G-CSF from inclusion bodies. This innovative method allows for the solubilization and refolding process to occur at ambient temperatures, with the purification involving reversed phase chromatography (RP), specifically RP-HPLC. The resultant G-CSF preparation is characterized by high purity and homogeneity, underscoring Scheckermann's impactful work in this field.
Career Highlights
Scheckermann has had an illustrious career, having worked with prominent companies like Biogenerix AG and Biogenerix GmbH. His experience in these organizations has contributed to his expertise in the development of biotechnological processes that enhance the production of therapeutic proteins.
Collaborations
Throughout his career, Scheckermann has collaborated with esteemed colleagues, including Walter Hinderer and Axel Angermann. These partnerships have fostered a creative environment conducive to research and innovation, enabling breakthroughs in protein production methodologies.
Conclusion
Christian Scheckermann's contributions to biotechnology, particularly in the realms of sialyltransferase and G-CSF production, represent significant advancements in the field. His patents reflect a commitment to innovation that continues to influence the development of essential therapeutic proteins, showcasing the vital role inventors play in modern science.