The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
Mar. 17, 2011
Applicants:
Walter Hinderer, Rodgau, DE;
Christian Scheckermann, Ehrenkirchen, DE;
Inventors:
Walter Hinderer, Rodgau, DE;
Christian Scheckermann, Ehrenkirchen, DE;
Assignee:
BioGeneriX GmbH, Ulm, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/00 (2006.01); C07K 1/16 (2006.01); C07K 1/18 (2006.01); C07K 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided is a method of obtaining biologically active recombinant human G-CSF from inclusion bodies, wherein the solubilization and refolding process can be performed at ambient temperature and the purification step comprises reversed phase chromatography (RP), in particular RP-HPLC. The G-CSF preparation so obtained is characterized by high purity and homogeneity.