Company Filing History:
Years Active: 2013-2022
Title: Christian Jorgensen: Innovator in Peptidomimetic Macrocycles and Gene Therapy
Introduction
Christian Jorgensen, based in Lattes, France, is an accomplished inventor known for his significant contributions to the fields of biochemistry and gene therapy. With a total of two patents under his name, Jorgensen demonstrates a commitment to advancing scientific understanding and practical applications in medicinal chemistry and therapeutic interventions.
Latest Patents
His notable patents include:
1. **Stapled peptides and uses thereof**: This invention involves peptidomimetic macrocycles that comprise at least one macrocycle-forming linker combined with specific amino acid sequences. These macrocycles are designed to include an α-helix structure and at least two natural or non-natural amino acids, which are linked by a macrocycle-forming linker. The invention provides methods for preparing these peptidomimetic macrocycles and discusses their applications as pharmaceutical compositions, specifically as inhibitors of inflammatory pathways.
2. **AAV vectors for in vivo gene therapy of rheumatoid arthritis**: This patent addresses the use of adeno-associated virus (AAV)-based gene therapy for rheumatoid arthritis (RA). The invention highlights recombinant AAV virions that efficiently deliver genes encoding therapeutic proteins directly to arthritic joints. Furthermore, it presents methods for utilizing these virions in in vivo gene therapy, paving the way for innovative treatments in RA management.
Career Highlights
Christian Jorgensen has worked with prestigious institutions, significantly impacting his field. Notable among these are the Academic Medical Center and the National Institute of Health and Medical Research. His experience at these organizations has enabled him to leverage advanced research facilities and collaborate with leading experts in medicine and biotechnology.
Collaborations
Throughout his career, Jorgensen has collaborated with prominent figures in the scientific community, including Paul Peter Tak and Guillaume Laconde. These partnerships have fostered a rich exchange of ideas and innovative solutions in the realm of medical research, enhancing the potential applications of his patented inventions.
Conclusion
Christian Jorgensen stands out as a forward-thinking inventor whose work on peptidomimetic macrocycles and AAV gene therapy represents crucial advancements in the medical field. His patents not only reflect his ingenuity but also hold promise for significant therapeutic interventions, particularly in managing conditions such as rheumatoid arthritis. Through his collaborations and career achievements, Jorgensen continues to inspire future innovations in life sciences.