Choy-Pik Chiu

Title: Choy-Pik Chiu: Innovator in Hepatocyte Differentiation

Introduction

Choy-Pik Chiu is a notable inventor based in Cupertino, CA, with a focus on stem cell research and hepatocyte differentiation. He holds a total of 6 patents, showcasing his contributions to the field of regenerative medicine.

Latest Patents

Chiu's latest patents include innovative protocols for making hepatocytes from embryonic stem cells. This disclosure presents a newly developed strategy for differentiating pluripotent stem cells into cells of the hepatocyte lineage. The protocols involve a multi-step process where cells are first differentiated into early germ layer cells, then into hepatocyte precursors, and finally into mature hepatocytes. The resulting cells exhibit morphological features and phenotypic markers characteristic of human adult hepatocytes. Additionally, they demonstrate cytochrome P450 enzyme activity, validating their potential for commercial applications such as drug screening and the manufacture of medicaments and medical devices for clinical therapy.

Career Highlights

Throughout his career, Choy-Pik Chiu has worked with prominent companies in the biotechnology sector, including Geron Corporation and Asterias Biotherapeutics, Inc. His work has significantly advanced the understanding and application of stem cell technology in medicine.

Collaborations

Chiu has collaborated with various professionals in his field, including Ramkumar Mandalam and Saadia Faouzi, who have contributed to his research endeavors.

Conclusion

Choy-Pik Chiu's innovative work in hepatocyte differentiation from embryonic stem cells positions him as a key figure in regenerative medicine. His patents and collaborations reflect his commitment to advancing medical science and improving therapeutic options.