Company Filing History:
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Years Active: 2011
Title: Chinnambedy Nainarappan Paramasivan: Innovator in Tyrosine Phosphatase Research
Introduction
Chinnambedy Nainarappan Paramasivan is a notable inventor based in Chennai, India. He has made significant contributions to the field of biotechnology, particularly in the development of mutant strains for research purposes. His work focuses on the modification of tyrosine phosphatase genes, which has implications for understanding virulence and pathogenesis in mycobacteria.
Latest Patents
Chinnambedy Nainarappan Paramasivan holds 1 patent. His patent provides mutant strains harboring a modified tyrosine phosphatase gene (mptpA or mptpB). The mutant strain is incapable of expressing the active tyrosine phosphatase. The invention outlines a method for developing the said mutant strain, where the mptpA or mptpB gene may be modified by replacing internal sequences with an antibiotic resistance marker gene. This modification disrupts the expression of the active gene. Furthermore, the invention includes a recombinant vector comprising the modified mptpA or mptpB, which can be utilized to develop mutant strains of mycobacteria. This research is crucial for assessing the role of tyrosine phosphatases MptpA and MptpB as potential targets for developing anti-tubercular drugs.
Career Highlights
Throughout his career, Chinnambedy Nainarappan Paramasivan has worked with esteemed organizations such as the Indian Council of Medical Research and the University of Delhi. His research has contributed to advancements in medical science, particularly in the fight against tuberculosis.
Collaborations
Chinnambedy has collaborated with notable colleagues, including Anil Kumar Tyagi and Ramandeep Singh. Their joint efforts have furthered research in the field of biotechnology and have led to significant findings in the study of mycobacterial diseases.
Conclusion
Chinnambedy Nainarappan Paramasivan is a distinguished inventor whose work in tyrosine phosphatase research has the potential to impact the development of new treatments for tuberculosis. His contributions to science and collaboration with other researchers highlight the importance of innovation in addressing global health challenges.