Ching-Che Huang

Title: Innovations in Anticancer Agents by Ching-Che Huang

Introduction

Ching-Che Huang is a notable inventor based in Taichung, Taiwan. He has made significant contributions to the field of medicinal chemistry, particularly in the development of anticancer agents. With a total of four patents to his name, Huang's work focuses on innovative compounds that show promise in cancer treatment.

Latest Patents

Huang's latest patents include the synthesis of 2-phenyl-4-quinolones and 2-selenophene-4-quinolones as anticancer agents. These compounds are converted into phosphates through a reaction with tetrabenzyl pyrophosphate, resulting in dibenzyl phosphates. These phosphates undergo hydrogenation to replace dibenzyl groups with hydrogen, followed by a reaction with Amberlite IR-120 (Na form) to form disodium salts. Preliminary screening results indicate that these phosphates exhibit significant anti-cancer activity. Additionally, novel intermediates such as 2-selenophene 4-quinolone and N,N-dialkylaminoalkyl derivatives of 2-phenyl-4-quinolones have also been synthesized, demonstrating substantial anticancer activities.

Career Highlights

Ching-Che Huang is affiliated with China Medical University, where he conducts his research and development work. His innovative approach to synthesizing anticancer agents has positioned him as a key figure in the field of medicinal chemistry. His patents reflect a commitment to advancing cancer treatment options through scientific innovation.

Collaborations

Huang collaborates with esteemed colleagues, including Sheng-Chu Kuo and Che-Ming Teng. These partnerships enhance the research efforts and contribute to the successful development of new therapeutic agents.

Conclusion

Ching-Che Huang's work in the synthesis of novel anticancer agents showcases his dedication to improving cancer treatment through innovative chemistry. His contributions are paving the way for future advancements in the field.