St. Louis, MO, United States of America

Chien-Huan Chen


Average Co-Inventor Count = 5.0

ph-index = 1


Location History:

  • Elkridge, MD (US) (2004)
  • St. Louis, MO (US) (2006 - 2010)

Company Filing History:


Years Active: 2004-2010

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3 patents (USPTO):Explore Patents

Title: The Innovations of Chien-Huan Chen: Pioneering Research in Hedgehog Signaling Pathway

Introduction

Chien-Huan Chen, an accomplished inventor based in St. Louis, MO, has made significant contributions to the field of biomedical research through his innovative work on the hedgehog signaling pathway. With three patents to his name, Chen's inventions have the potential to influence treatments for various tumors by modulating essential biological processes.

Latest Patents

Among his groundbreaking inventions, Chen's latest patents focus on the modulation of the hedgehog-mediated signaling pathway. These patents describe transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. The innovations include hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors, as well as methods for identifying compounds that act as phosphatase inhibitors. Furthermore, these patents outline novel methods for treating tumors in subjects by modulating the phosphorylation of these crucial transcription factors.

Career Highlights

Chien-Huan Chen has had a distinguished career, working with prestigious institutions such as Johns Hopkins University and Baylor College of Medicine. His research has garnered attention not only for its scientific merit but also for its potential applications in medicine, particularly in oncology.

Collaborations

Throughout his career, Chen has collaborated with other respected figures in the field. Notable coworkers include Philip Arden Beachy and Ming-Jer Tsai, both of whom have been instrumental in advancing research associated with the hedgehog signaling pathway. These collaborations underscore the collective effort required to drive innovation in complex biological systems.

Conclusion

Chien-Huan Chen's work exemplifies the essence of scientific innovation, with his patents promising to pave the way for new therapeutic approaches in cancer treatment. His dedication to understanding and modulating crucial biological mechanisms continues to inspire future research and development in the field.

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