Company Filing History:
Years Active: 2010-2014
Title: Cheryl Hill: Innovator in Blood Group Antigen Removal
Introduction
Cheryl Hill is a prominent inventor based in North Andover, MA (US). She has made significant contributions to the field of enzymatic processes, particularly in the removal of blood group antigens. With a total of 3 patents to her name, her work has the potential to impact blood transfusion practices and improve patient outcomes.
Latest Patents
Cheryl's latest patents focus on the enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products. This innovative process converts these cells to non-A and non-B reactive cells. The patents detail the use of unique α-N-acetylgalactosaminidases and α-galactosidases that exhibit superior kinetic properties for effectively removing the immunodominant monosaccharides of the blood group A and B antigens. The preferred enzymes demonstrate specific substrate activity and optimal performance at neutral pH, leading to improved enzymatic conversion of red blood cells. Notably, her methods utilize significantly lower amounts of recombinant glycosidase enzymes compared to previous techniques, achieving complete sero-conversion of all blood group A and B red cells.
Career Highlights
Cheryl Hill is associated with Velico Medical, Inc., where she continues to advance her research and innovations. Her work is pivotal in enhancing the safety and efficacy of blood products.
Collaborations
Cheryl has collaborated with notable professionals in her field, including Henrik Clausen and Humberto De La Vega. These partnerships have contributed to the development and refinement of her innovative processes.
Conclusion
Cheryl Hill's contributions to the field of enzymatic blood group antigen removal are groundbreaking. Her patents reflect a commitment to improving medical practices and patient care through innovative solutions.