The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2010
Filed:
Sep. 20, 2002
Henrik Clausen, Holte, DK;
Humberto DE LA Vega, Salem, MA (US);
Cheryl Hill, North Andover, MA (US);
Qiyong Peter Liu, Newton, MA (US);
Henrik Clausen, Holte, DK;
Humberto de la Vega, Salem, MA (US);
Cheryl Hill, North Andover, MA (US);
Qiyong Peter Liu, Newton, MA (US);
Velico Medical, Inc., Beverly, MA (US);
Abstract
This invention relates to enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products, and thereby converting these to non-A and non-B reactive cells. The invention further relates to using unique αN-acetylgalactosaminidases and α-galactosidases with superior kinetic properties for removing the immunodominant monosaccharides of the blood group A and B antigens and improved performance in enzymatic conversion of red blood cells. The preferred unique α-N-acetylgalactosaminidases and α-galactosidases exhibit the following characteristics: