Chengang Xiang

Title: Chengang Xiang: Innovator in Hepatocyte Reprogramming

Introduction

Chengang Xiang is a prominent inventor based in Beijing, China. He has made significant contributions to the field of cellular reprogramming, particularly in the conversion of non-hepatocyte cells into functional hepatocyte-like cells. His innovative methods have the potential to advance pharmaceutical applications and improve drug metabolism.

Latest Patents

Chengang Xiang holds a patent for "Methods for reprogramming non-hepatocyte cells into hepatocyte cells." This patent describes a method for inducing the reprogramming of non-hepatocyte cells into cells with functional hepatic drug metabolizing and transporting capabilities. The process involves inducing non-hepatocyte cells to express or overexpress hepatic fate conversion and maturation factors. These cells are then cultured in various media for a sufficient period to develop hepatocyte-like properties. The induced hepatocytes, known as iHeps, exhibit superior drug metabolizing activity compared to those obtained through prior methods.

Career Highlights

Chengang Xiang has worked with notable institutions such as the Beihao Stem Cell and Regenerative Medicine Translational Research Institute and Peking University. His work has focused on advancing the understanding of cell reprogramming and its applications in regenerative medicine.

Collaborations

Chengang has collaborated with esteemed colleagues, including Hongkui Deng and Yuanyuan Du. Their joint efforts have contributed to the advancement of research in cellular reprogramming and its implications for medical science.

Conclusion

Chengang Xiang's innovative work in the field of hepatocyte reprogramming showcases his commitment to advancing medical science through cellular research. His contributions have the potential to significantly impact pharmaceutical applications and improve drug metabolism.