Cheng-Wen Wu

Title: Innovations of Cheng-Wen Wu in Lung Cancer Therapy

Introduction

Cheng-Wen Wu is a notable inventor based in Miaoli County, Taiwan. He has made significant contributions to the field of cancer research, particularly in the development of methods for assessing lung cancer therapy efficacy. With a total of four patents to his name, his work is paving the way for advancements in cancer treatment and prognosis.

Latest Patents

One of his latest patents is a "Rapid efficacy assessment method for lung cancer therapy." This invention discloses a method for rapid assessment of lung cancer therapy efficacy in a few days instead of weeks, as is typical with conventional imaging methods. This innovative approach can also detect cancer relapse and improve the current TNM cancer staging method for more accurate prognosis. The rapid assessment is based on detecting circulating cancer cells in body fluid with a high positive detection rate, achieved through qPCR amplification of multiple marker genes identified by an in silico search of DNA sequence databases. Additionally, this invention includes a scoring method to calculate cancer cell load based on qPCR results, correlating the amount of circulating cancer cells in lung cancer patients and predicting treatment outcomes.

Another significant patent is related to "Collapsin response mediator protein-1." This invention is based on the discovery of an association between Collapsin Response Mediator Protein-1 (CRMP-1) and tumor metastasis. The level of CRMP-1 protein or mRNA can serve as an indicator of cellular invasiveness and a test compound's ability to alter this invasiveness. Furthermore, the level of CRMP-1 protein can be modified to reduce invasiveness, showcasing the potential for therapeutic applications.

Career Highlights

Cheng-Wen Wu has worked with esteemed institutions such as the National Health Research Institutes and Academia Sinica. His experience in these organizations has contributed to his expertise in cancer research and innovation.

Collaborations

Cheng-Wen Wu has collaborated with notable colleagues, including Konan Peck and Pan-Chyr Yang. Their joint efforts have further advanced the research and development of cancer therapies.

Conclusion

Cheng-Wen Wu's innovative work in lung cancer therapy is making a significant impact in the medical field. His patents reflect a commitment to improving cancer treatment and patient outcomes.