The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2009
Filed:
Dec. 31, 2005
Konan Peck, Taipei, TW;
Yuh-pyng Sher, Taipei, TW;
Jin-yuan Shih, Taipei, TW;
Pan-chyr Yang, Taipei, TW;
Cheng-wen Wu, Miaoli County, TW;
Konan Peck, Taipei, TW;
Yuh-Pyng Sher, Taipei, TW;
Jin-Yuan Shih, Taipei, TW;
Pan-Chyr Yang, Taipei, TW;
Cheng-Wen Wu, Miaoli County, TW;
National Health Research Institutes, Miaoli County, TW;
Abstract
The present invention discloses a method for rapid assessment of lung cancer therapy efficacy in a few days instead of weeks by conventional imaging methods. This method can also be used to detect relapse of the cancer and to improve the current TNM cancer staging method for more accurate prognosis. The rapid assessment of therapy efficacy is based on detecting circulating cancer cells in body fluid with high positive detection rate. The high positive detection rate is achieved by using qPCR amplification of multiple marker genes identified by in silico search of DNA sequence database. This invention also discloses a scoring method to calculate the cancer cell load based on qPCR results to correlate the amount of circulating cancer cells in lung cancer patients and predict the treatment outcomes.