Blue Bell, PA, United States of America

Charlotte C Ip



Average Co-Inventor Count = 8.9

ph-index = 3

Forward Citations = 152(Granted Patents)


Company Filing History:


Years Active: 1997-2007

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3 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Inventor Charlotte C. Ip

Introduction

Charlotte C. Ip is a notable inventor based in Blue Bell, Pennsylvania, renowned for her contributions to vaccine development. With a remarkable portfolio of three patents, she has made significant strides in the field of microbial polysaccharides and immunology. Her expertise and innovation aim to enhance vaccine efficacy against infectious diseases.

Latest Patents

Charlotte’s latest patents reflect her focus on high molecular weight polysaccharides and their applications in vaccines. One of her patents describes a high molecular weight polysaccharide intracellular adhesin (SAE) antigen, characterized by a unique structure of poly-1,6,β-2-amidoglucopyranoside, which is variably substituted with N-acetyl and O-succinyl groups. This antigen is pivotal for use in vaccines, whether utilized alone, conjugated to an immunogenic protein, or in conjunction with immunogenic adjuvants.

Another of her significant innovations involves the process for making type-specific capsular polysaccharides from Streptococcus pneumoniae. This novel method yields polysaccharide preparations having an average of fewer than 1000 oligosaccharide repeat units per molecule and minimal contamination by group-specific C-polysaccharide. These polysaccharide products play a crucial role in the production of vaccines, particularly in creating covalent conjugates linked to T-cell stimulatory carrier proteins. The resulting vaccines are vital for preventing infections and diseases linked to Streptococcus pneumoniae.

Career Highlights

Charlotte currently works at Merck & Company, Inc., a globally recognized leader in pharmaceutical products. Her research and patented innovations continue to impact vaccine technology significantly, particularly in combatting infectious diseases through improved immunogenic responses.

Collaborations

Throughout her career, Charlotte has collaborated with esteemed colleagues in her field, including Peter J. Kniskern and William J. Miller. These collaborations have fostered innovative research, pooling their knowledge and expertise to advance vaccine development and improve public health outcomes.

Conclusion

Charlotte C. Ip stands out as a pioneering inventor whose work in vaccine development holds promise for future advancements in the medical field. With her ongoing research and innovative patents, she continues to contribute to the fight against infectious diseases, enhancing the efficacy of vaccines and setting a high standard for scientific discovery.

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